![]() Orthologous to human CLCNKA (chloride voltage-gated channel Ka) and CLCNKB (chloride voltage-gated channel Kb) PARTICIPATES IN amiloride pharmacodynamics pathway bendroflumethiazide pharmacodynamics pathway bumetanide pharmacodynamics pathway INTERACTS WITH (4-chloro-2-methylphenoxy)acetic acid 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid 6-propyl-2-thiouracil.2 Manual for CLC Sequence Viewer Windows, Mac OS X and Linux SeptemThis software is for research purposes only. Human ortholog(s) of this gene implicated in Bartter disease type 3 Bartter disease type 4b Gitelman syndrome hypertension and sensorineural hearing loss. Located in apical plasma membrane basolateral plasma membrane and endoplasmic reticulum. Involved in several processes, including body fluid secretion response to calcium ion and response to water deprivation. Enables chloride channel activity and voltage-gated monoatomic ion channel activity. ![]()
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